Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKRKIGLAMSLVIAAGTILGACGNSEKSSGSGEGKNKFSVAMVTDVGGVDDKSFNQSAWEGIQAFGKENGLKKGKNG-YDYLQS-KSDADYTTNLNKLAR-ENFDLIYGVGYLMEDSISEIADQRKNTNFAIIDAVVD-KDNVASITFKEQEGSFLVGVAAALSSK--------SGKIGFVGGMESELIKKF-EVGFRAGVQAVNPKAVVEVKYAGGFDKADVGKATAESMYKSGVDVIYHSAGATGTGVFTEAKNLKKEDPKRDVWVIGVDKDQYAEGQVEGTDDNVTLTSMVKKVDTVVEDVTKKASDGKFPGGETLTYGLDQDGVGISPSK----QNLSDDVIKAVDKWKKKIIDG-LEIPATEKELKTFKAE 4IIL Chain:A ((31-344)) ------------------------------------RAVRIAVFV-PGFRHDSPVYAMLCDGVERAVTQERAT-GRSIGLDIIEAGPNQALWREKLAHLAAEQRYRLIVSSNPALPHVLEPILRQFPLQRFLVLDAYAPQEHSLITFRYNQWEQAYLAGHLSALVSASAMRFANADKKIGLIAGQSYPVMTQTIIPAFLAGARAVDPAFEVDVRVVGNWYDAAKSADLARILFHEGVDVMMPICGGANQGVLAAAREL-------GFYVSWFDDNGYAR------APGYVVGSSVMEQERLAYEQTLRCIRGELPSAGAWTLGVKDGYVRFIEEDPLYLQTVPEPIRVRQSALLRRIQSGELTLP------------

General information: TITO was launched using: RESULT: Template: 4IIL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1761 20454 11.61 69.10 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 11.61 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_4IIL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IIL-query.scw PDB file : Tito_Scwrl_4IIL.pdb: