Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLVLIGGGYGNMRVLHRLLPNQLPDDVSITLIDRNPYHCLKTEYYALAAGTISDHHIRVSFPEHP---RLDVQYGDITSIDIVQKQVLFQ--DR--EPISYDDAIIGLGCEDKYHNVPGAPEFTYSIQTIDQSRETYQKLNNLSANATVAIVGAGLS-------------------------GVELASELRESRD------DLNIILFDRGNLILSSFPERLSKYVQKWFEEHGVRIINRANITKVEEG-VVYNHDDPISADAIVWTAGIQPNKVVRDLDVE-KDAQGRIVLTPHHNLPGDEHLYVVGDCASLPHAPSAQLAEAQAEQIVQILQKRWNGEA-LPESMPQFKLKGVLGSL-GK-KAGFGLVADRPLIGRVPRMLKSGLLWMYKHHNG 3H8L Chain:A ((2-357)) -TKVLVLGGRFGALTAAYTLKRLV-GSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVDLSEALPEKGIQFQEGTVEKIDAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATELVKGWDKYGYSVCEPEFATKLREKLESF-QGGNIAI-GSGPFYQGHNPKPKVPENFVPNADSACEGPVFEMSLMLHGYFKKKGMLDKVHVTVFSPGE-YLSDLSPNSRKAVASIYNQLGIKLVHNFKIKEIREHEIVDEKGNTIPADITILLPPYTGNPALKNSTPDLVDDGGFIPTDLNMVSIKYDNVYAVGDANSMTVPKLGYLAVMTGRIAAQHLANRLGVPTKVDKYYP----TIVCVADNPYE---------------------------------

General information: TITO was launched using: RESULT: Template: 3H8L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1693 -1250 -0.74 -3.99 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -0.74 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_3H8L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H8L-query.scw PDB file : Tito_Scwrl_3H8L.pdb: