Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MKSCKQLIV-----CSL-AAILLLI-------PSVSFAADSNISVKLLNYIGNKSSISLSPTGFYKVTGDNVAVTDRFAGASRYETATLASNSQWKNPNTVILVNRDIFIDALPVIPLAKKLNAPVLFTQPDTLTKTTERQIAKF-NPDNILIIGGARSISKDVENKLKSYGAVKRISGKNRYVLSENIAKQMGSYDKAIVVTGRVFQ-DALAIAPYAAAHGYPILLTEKDKLPD--YDLPKQVIIIGSSFSVSDSVENQI----KKTSTVQ----RIPGST-RYELTANI--IKQLKLKAD-----KVVMTNGTKYADVLIGASLASKKNSQILFVKQDSVPAAAKSITKDKATYAYD--FIGSTSSISAEVENSLADEFYLADGGTYNLKINSGKLNLENIKTYGNSLR-IKPENYSTSN---RISLDGKQYLGTVNFSIESTKYIRPVNENIPFEDY--LKGVIPNEMPASWSLEALKAQTVAARTYSITKTGTTVPDTTAFQVYGGYSWNSNTNKAVEQTKGKVLK------YNGSLITAAYSSSNGGYTEASNEVW--SSSVPYLIAKKDTKDPQIGWTLTLSKQQL--------------DTKSLDLTKPSSWWSSATETDSARLSGVKNWILKNKETSADSV-------KIASIDDLSFSGTTQGQRAKTASMKVKYFVKSSTGSYNLSKITTISVPTSELRTMIGATVFKSTYVTVKKDTSKYTISGKGYG-----HGIGMSQYGAKARAEAGDSYSSILKFYYPGTTLTSY------- 4LXR Chain:A ((1-773)) SFGRDACSEMSIDGLCQCAPIMSEYEIICPANAENPTFRLTIQPKDYVQIMCNLTDTTDYQQLPKKLRIGEVDRVQMR-RCMLPGHTPIASILDYLGIVSPTTLIFESDNLGMN-ITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLR-QMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAELQSLPGDLFEHSTQITNISLGDNLLKTLPATLL---EHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGI--------SGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHND----IDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYNNISSLG------YEDLAFLSQNRLHVNMTHNKIRRIALPEDVNNNLVHVDLND---------NPLVCDCTILWFIQLVRGVHKPQYSRQFKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKNMQLMELHLENNTLLRLPSANTPGYESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNWRSVKLSGNPWMCDCTAKPLLLFTQDNFERIGD--RNEMMCVNAPTRMVELSTNDICP

General information: TITO was launched using: RESULT: Template: 4LXR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3598 132492 36.82 197.75 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 36.82 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.209

(partial model without unconserved sides chains): PDB file : Tito_4LXR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LXR-query.scw PDB file : Tito_Scwrl_4LXR.pdb: