Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQQDIKQKVLDVLDHHKVGSLATVQ-KG-KPHSRYMTFFHDGLTIYTPTSKETHKAEEIENNPNVHILLGYDCEGFGDAYVEVAGKAKINNSAELKDKIWSSKLERWFD--GKDDPNLVILEIEPEDIRLMNAGEKTPVSLEL 2IAB Chain:A ((10-139)) --AKQRIQDTLNRLELDVDAWVSTAGADGGAPYLVPLSYLWDGETFLVATPAASPTGRNLSETGRVRLGIGP-----TRDLVLVEGTALPLEPAGLPDGVGDTFAEKTGFDPRRLTTSYLYFRISPRRVQAWREANE-------

General information: TITO was launched using: RESULT: Template: 2IAB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 552 -46498 -84.23 -369.03 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -84.23 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.399

(partial model without unconserved sides chains): PDB file : Tito_2IAB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IAB-query.scw PDB file : Tito_Scwrl_2IAB.pdb: