Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTALLVIDIQNDYFPNGKMALTNPEKAAQNAAKLLSHFRNTGAPVFHVQHITEGNI----------AHFFHPNTEGVEIHESVRPLEKETVI------VKHMPNSFFNTDLNGKLQEEGVKELVVCGMMSHMCIDATVRSAVEHGYVCQVVEDACATTTLQIEDKIVPAEHVHYAFMAALNGVYATVKTTEAFLK 1IM5 Chain:A ((2-179)) PEEALIVVDMQRDFMPGGALPVPEGDKIIPKVNEYIRKFKEKGALIVATRDWHPENHISFRERGGPWPRHCVQNTPGAEFVVDLPED--AVIISKATEPDKEAYSGFEGTDLAKILRGNGVKRVYICGVATEYCVRATALDALKHGFEVYLLRDAVKGIKPED----------EERALEEMKSRGIKIVQ------

General information: TITO was launched using: RESULT: Template: 1IM5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 873 -136783 -156.68 -844.34 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -156.68 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_1IM5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IM5-query.scw PDB file : Tito_Scwrl_1IM5.pdb: