Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIELEVVIRTVASFGLLLIAERILG-KQTISQMTIFDFIAAITLGAIAAG-LAYNTSIKPHNMAIS-FSIFVLTIFLISFLSIKNRKLRKFFAGDPTVLIQN-GK-ILESNMRKMRYTLDYLNQQLREKEIFNIEEV-LFAILETNGQLTVLRKPQFRHVTKQDLMIAVNQEQRLPIELIM-DGEIIENNLKQNRLTESWLLEELRKRDIKVKETVYAVLLGNGDIYVDQYK-DHISVPMDKE--------- 3WOZ Chain:A ((645-869)) TEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRIELKRLCEIFTRMFAD-----PHGKVFSMF-----LETLVDFIQVHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDITRESFPNDLQFNI--LMRFTVDQTQ---------------TPSLKVKVAILKYIETLAKQMDPRDFTNSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHN

General information: TITO was launched using: RESULT: Template: 3WOZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 821 -78519 -95.64 -377.50 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -95.64 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.291

(partial model without unconserved sides chains): PDB file : Tito_3WOZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WOZ-query.scw PDB file : Tito_Scwrl_3WOZ.pdb: