Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------MS-DFA-FKLYEYNVWANQQIFNRLKELPKEIYHQEIQSVFPSISHVLSHVYLSDLGWIEVFSGKTLSDALALAEQLKEQ------TEAKEIEEMEDLFLRLSERYILFLQQKEQLNKPLQIQNPSSGIMKTTVSELLPHVVNHGTYHRGNITAM-LRQAGYASAPTDYGLYLFMTKTEKA 2RD9 Chain:A ((5-193)) KIHHHHHHENLYFQGMNFQMNEAIQLLERTPKTLEVFLEGLSDSWHQCNEGYETWTVYEVVVHLIEAEKTNWIPRLRFILQEGEHKPFPAFDRFSHLNQSNAVPISERFKEFQQLRKENLNTLRSLVQSEADLERTGAHPAFGVVKVRELLSAWVVHDLTHIAQIVRSMAKRYD--TDVGPWKEYLGILND---

General information: TITO was launched using: RESULT: Template: 2RD9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 529 -56716 -107.21 -339.61 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -107.21 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.281

(partial model without unconserved sides chains): PDB file : Tito_2RD9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2RD9-query.scw PDB file : Tito_Scwrl_2RD9.pdb: