Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELKHLPKYKHITEHAETYANIDAGSLELFLSLFDISKKMNHVMEHYFAGRGLSEGKFKILMLLFDAKDHRLSPTELAKRSNVTKATITGLLDGLARDGFVSRRHHTEDKRKISIELTTEGKARLEQFLPGHFSKISAVMENYSDEEKDMFVKMLGDLFERLSVFKD 3CDH Chain:A ((10-149)) ---------------------DTFVSGYLLYLLAASSEEASAQFHDHIRAQGLRVPEWRVLACLVDN--DAMMITRLAKLSLMEQSRMTRIVDQMDARGLVTRVA------RVRVRLTDDGRALAESLVASARAHETRLLSALADTDAARIKGVLRTLLDVLD----

General information: TITO was launched using: RESULT: Template: 3CDH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 406 -66701 -164.29 -497.76 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -164.29 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.577

(partial model without unconserved sides chains): PDB file : Tito_3CDH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CDH-query.scw PDB file : Tito_Scwrl_3CDH.pdb: