Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERISWNQYFMAQSHLLALRSTCPRLSVGATIVRDKRMIAGGYNGSIAGGVHCADEGCLMIDDHCAR--TIHAEMNAILQCSKFGVPTDGAEIYVTHYPCIQCCKSIIQAGIKTVYYAEDYKTHPYAQELFEQAGVTVEQVELDEMIVDLKNREKLSFVAGLIGKLADAGLAEEELKKIHEQANTLFTSYV 4P9C Chain:C ((12-138)) ---------YMKTAELFSQVSNCKRMKVGAIVVKNGSILAHGWNGTPSG----FHTNCCELEDGSTNPFVLHAEQNALVKMAKSSESIDGSELFCTHSPCPDCSKMIAQAGVKKVYYRNEYRITD-GIDVLQQLGVEVEKM--------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4P9C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 648 -19758 -30.49 -158.06 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain C : 0.71 3D Compatibility (PKB) : -30.49 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.587

(partial model without unconserved sides chains): PDB file : Tito_4P9C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P9C-query.scw PDB file : Tito_Scwrl_4P9C.pdb: