Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKKALIFTVIFGIIFLAVLLVSASIYKSAMAQKEEGHEAAAAEAKKETDLAHVDQVETFVGKEKYYVVKGTDKKGTALYVWVPADKKAKILSKEAKEGISEDKAAKIIKDEG------LVSKQKEVHLAREGN---------VLLWEVTYLDK---EG-------QYSLSYVDFTTGKILKNITP 5COZ Chain:A ((270-357)) -----------------------------------------------------------------------------------------------TGEILHPSSILSKEVDKLKKYVTSGDIEVSEISLEYMLFADKNETYDIKPVWVVYYYQNQLVTGENSYTQKMALYDVYDAYTGEEYRI---

General information: TITO was launched using: RESULT: Template: 5COZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 133 -1934 -14.54 -30.69 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : -14.54 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.747

(partial model without unconserved sides chains): PDB file : Tito_5COZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5COZ-query.scw PDB file : Tito_Scwrl_5COZ.pdb: