Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNEIAEVLPESMKNALSEIPEQQWLEIEEVRIRINR---PVELIRRGQPVYLSYAGTAEDAHLILSRLSNYSMYTLEEE--LKKGYVTIRGGHRVGLAGRVITENGGVKGLRDIASFNIRIARQKLGIAEPLLPYLYQN---SWLNTLIIGPPQTGKTTLLRDLARLSSTGKKNMLPVKTGIVDERSEIAGCLRGIPQHQFGQRIDVLDACPKAEGLMMMIRSMSPEVMIVDEIGRMEDTDALLEALHAGVSVIVSAHGWSISDLMKRPSLKRLWEERAFDRYLELSRAKGPGTVSQIYDKDGNVLSRTTGVKTC 4KSR Chain:A ((126-398)) ----------LINAMLGE---AIKEGASDIHIETFEKTLSIRFRVDGVLREVL-APSRKLSSLLVSRVKVMAKLDIAEKRVPQDGRISL--AVDVRVSTMPSS-HGERVVMRLLDK-----DLHSLGMTAHNHDNFRRLIKRPHGIILVTGPTGSGKSTTLYAGLQELNSSER-----NILTVEDPIEFDIDG--IGQTQVNPR----VDMTFARGLRAILR-QDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAVGAVTRLRDMGIE----------------------------------------

General information: TITO was launched using: RESULT: Template: 4KSR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1019 8748 8.58 37.55 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 8.58 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.379

(partial model without unconserved sides chains): PDB file : Tito_4KSR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KSR-query.scw PDB file : Tito_Scwrl_4KSR.pdb: