Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKQLIQSEEEFKRIAEQEGVFVFLKHSTTCPISQAAFHEFDAFANQH-EDVPAYYLQVQEARPLSNFIAETYGVKHESPQIFIIQNGEVKWHTSHSQITEAAIEQHLS 2YZU Chain:A ((8-102)) -------TDQNFDETLGQHPLVLVDFWAEWCAPCRMIAPILEEIAKEYEGKLLVAKLDVDENPK----TAMRYRVMS-IPTVILFKDGQPVEVLV-GAQPKRNYQAKI-

General information: TITO was launched using: RESULT: Template: 2YZU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 368 -28168 -76.54 -299.66 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -76.54 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.612

(partial model without unconserved sides chains): PDB file : Tito_2YZU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YZU-query.scw PDB file : Tito_Scwrl_2YZU.pdb: