Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPVEKIQIRRDYVLQYMVNNDYSLNQLALEIGVSPATLSRVLNGER-RPGQLVIGKMLHYFNLKFEDLFYYDFVDKSQ 3B7H Chain:A ((10-73)) ----------EHLMELITQQNLTINRVATLAGLNQSTVNAMFEGRSKRPTITTIRKVCGTLGISVHDFFDFPPY----

General information: TITO was launched using: RESULT: Template: 3B7H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 192 -38814 -202.16 -616.10 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -202.16 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.563

(partial model without unconserved sides chains): PDB file : Tito_3B7H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3B7H-query.scw PDB file : Tito_Scwrl_3B7H.pdb: