Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHDKPEEEVV--EEIVKVAGMFAVDAITTNNELFIA--PMAKACERLGLR--GAGVQAAENARDKNKMRAAFNRAGVKSIKNK--RVTTLEDFRAALQEIGTPLILKPTYLASSIGVTLIKEMETAEAEFNRVNEYLKSINVPKAVTFEAPFIAEEFLQGEYDDWYETSGYSDYISIEGIMA-DGEYFPVAIHDKTPQIGFTETSHITPSI-LDDDAKRKIVEAAKKANEGLGLENCATHTEIKLMKNREAGLIESAARFAGWNMIPNIKKVFGVDMAQLLLDVLCFGKEADLPKGLLEQEPCYVADCHLYPQHFKENGQLPETAVDF--VIESIDIPDGVLKGDTEI--VSFSAAEAGTSVDLRLFEAFNSIAAFELKGSNSGDVAESIKQIQQQAKLTAKYALPV 1ULZ Chain:A ((1-413)) -MVNKVLVANR-G-EIAVRIIRACKEL-GIP-----TVAIYNEVESTARHV-----------------KLADEAYMIGT---DPLDTYLNKQRIINLALEVGADAIHPGYGFLAENAEFAKMCEEAGITFIGPHWKVIELMGDKARSKEVMKKAGVPVVPGSDGVLKSLEEAKALAREIGYPVLLKATAGGGGRGIRICRNEEELVKNYEQASREAE------KAFGRGDLLLEKFIENPKH-----------IEYQVLGDKHGNVIHLGERDCSIQRRNQKLVEIAPSLILTPEKREYYGNIVTKAAKEIGYY-NAGTMEFIADQEGNLYFIEMNTRIQVEH--PVSEMVTGIDIVKWQIKIAAGEPLTIKQEDV-----------KFNGYAIECRINA-EDPKKNFAPST--RVIERY-YVPGGFGIRVEHAAARGFEVTPY-YDSMIAKLITW--APTWDEAVERMRAALETYEITG------

General information: TITO was launched using: RESULT: Template: 1ULZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2203 79038 35.88 198.09 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 35.88 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_1ULZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ULZ-query.scw PDB file : Tito_Scwrl_1ULZ.pdb: