Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPKVSVIMTSYNKSDYVAKS---ISSILSQTFSDFELFIMDDNSN--EETLNVIRPFLNDNRVRFYQSD---------ISGVKERTEKTRYAALINQAIEMAE---------GEYITYATDDNIYMPDRLLKMVRELDTHPEKAVIYSASKTYHLNENRDIVKETVRPAAQVTWNAPCAIDHCSVMHRYSVLEKVKEKFGSYWDESPAFYRIGDARFFWRVNHFYPFYPLDEELDLNYITDQSIHFQLFELEKNEFVRNLPPQRNCRELRESLKKLGMG 1V84 Chain:A ((2-129)) LPTIHVVTPTYSRPVQKAELTRMANTL-LHV-PNLHWLVVEDAPRRTPLTARLLRDT--GLNYTHLHVETPRNYKLRIPRG---------TMQ-RNLALRWLRETFPRNSSQPGVVYFADDDNTYSLELFEEMRS------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1V84.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 335 -1237 -3.69 -12.62 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -3.69 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.610

(partial model without unconserved sides chains): PDB file : Tito_1V84.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V84-query.scw PDB file : Tito_Scwrl_1V84.pdb: