Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIRTLLLSALVAGALSCGYPTYEVQHDVSRVVGGQEASPNSWPWQVSLQYLS-SGKWHHTCGGSLVANNWVLTAAHCISN---SRTYRVLLGRHSLSTSESGSLAVQVSKLVVHEKWNAQKLSNGNDIALVKLASP----VALTSKIQTACLPPAGTILPNNYPCYVTGWGRLQTNG-ATPDVLQQGRLLVVDYATCSSASWWGSSVKTNMVCAGG-DGVTSSCNGDSGGPLNCQASNGQWQVHGIVSFGSTLGCNYPRKPSVFTRVSNYIDWINSVIAKN 3MHW Chain:U ((1-247)) ------------------------------IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSAD-LAHHNDIALLKIRSKEGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSL-QGRMTLTGIVSWGR--GCALKDKPGVYTRVSHFLPWIRSHTKE-

General information: TITO was launched using: RESULT: Template: 3MHW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -164046 for 2043 contacts (-80.3/contact) + 2D Compatibility (PS) -26061 + (NN) -15274 + (LL) 2652 1D Compatibility (HY) -18000 + (ID) 4100 Total energy: -224829.0 ( -110.05 by residue) QMean score : 0.408

(partial model without unconserved sides chains): PDB file : Tito_3MHW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MHW-query.scw PDB file : Tito_Scwrl_3MHW.pdb: