Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKFDISVLSVAPLRQGETMKQGIDSAVSLAKAVDNMGYKRIWFAEHHNHDA---YASAATVSIVQHILANTKDIRVGSGGIMLPN-HSPLIVAEQFGTLETLYPNRVDLALGRAPGTDQKTADVIRRSN--HNGVFFFEREVNDILRFVGDKS------VQG---EVRAYPGIGTHVPVFVLGSSTDSAEIAAKLGLPYAFGAQFSPHSME-EALSIYRENFQPSSY-LQEPYVIACINVIAAESIDEASFISASHLQVYIDIYTNNLSKLIPPTENFLESLSQFELEILHSRL-GYTIMGDRETIRRELIDFQQMYHADELIVLSNIYELSKEIQSYEILKQVVDELFKKRMEQL 1RHC Chain:A ((1-330)) -MKTQIGYFASLEQ-------YRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQSAQAWAWMGAALQATKKVFISTCITCPIMRYNPAIVAQTFATLRQMYPGRVGVAVGAG--EAMNEVPVTGEWPSVPVRQDMTVEAVKVMRMLWESDKPVTFKGDYFTLDKAFLYTKPDDEVPLYFSGMGPKGAKLAGMYGDHLMTVA-AAPSTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPSMF-KYKVYD-PKE-VQLH-AN--LVHCDTIKENYMCATDAEEMIKEIERFK-EAGINHFCLGNSSP---DVNFGIDIF-KEVIPAVRD-----

General information: TITO was launched using: RESULT: Template: 1RHC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1817 -200464 -110.33 -642.51 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -110.33 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_1RHC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RHC-query.scw PDB file : Tito_Scwrl_1RHC.pdb: