Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKQYWFIILTYIIMQFSALIAIPLLFKFGYAGGQPTDENMLHAQGLWSVISFIACLV-------------VVLLILRT----VPKETLRNGQKDSIGLSILWAIAGFFIALFSQGIAGSIEYYVFGIGRESENTQAILDVIQAVPLMIIVSSIVGP-----ILEEIIFRKIIFGALYEKTNFFF---AGLISSVIF---GIVHADLKHLLLYTAMGFTFAFLYARTKRIWVPIFAHLMMNTFVVIMQLEPVRNYLEQQSTQMQLIIGGLFL--------------- 4TQ3 Chain:A ((15-301)) --SKYLRLLRPVAWLCFLLPYAVGFGFGITPNASLQHAVLGLLSFAFWMAFSFTINALYDRDVDRLHDGLNLSMQPLVTGEISVREAWLYCIAFLALSLATAAAINEKFFLAMLGANIIGYVYSAPPRFKAWPVMDVICNALAAVLAFYAGLSIGGAEVPIAIYPAAFFLAATFYIPTAVSDYEFDKKAGLKNTPVFFGPERALKSLYPLSAITVILWAYVFLMA--ERIEIKVISPLIIAYTLIYTFIINSRWDGEKLNVSPNLILTPFGIISALFIAYGFAVISV

General information: TITO was launched using: RESULT: Template: 4TQ3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1069 -198840 -186.01 -828.50 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -186.01 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.239

(partial model without unconserved sides chains): PDB file : Tito_4TQ3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TQ3-query.scw PDB file : Tito_Scwrl_4TQ3.pdb: