Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRYRTLLFDVDDTILDFQAAEALALRLLFEDQNIPLTND-MKAQYKTINQGLWRAFEEGKMTR---DEVVNTRFSALLKEYGYEADGALLEQKYRRFLEEGHQLIDGAFDLISNLQQQFDLYIVTNGVSHTQYKRLRDSGLFPFFKDIFVSEDTGFQKPMKEYFNYVFERIPQFSAEHTLIIGDSLTADIKGGQLAGLDTCWMNPDMKPN----V--P-EIIPTYEIRKLEELYHILNIENTVSC 3UMC Chain:A ((19-252)) FQGMRAILFDVFGTLVDWRSSLIEQFQALERELGGTLPCVELTDRWRQQYKPAMDRVRNGQAPWQHLDQLHRQSLEALAGEFGLALDE-ALLQRITGFW-HRLRPWPDTLAGMHALKADYWLAALSNGNTALMLDVARHAGLP--WDMLLCADLFGHYKPDPQVYLGACRLL-DLPPQEVMLCAAHN-YDLKAARALGLKTAFIARPLEYGPGQSQDLAAEQDWDLIASDLLDLHRQLAA------

General information: TITO was launched using: RESULT: Template: 3UMC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1078 -147214 -136.56 -660.15 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -136.56 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.547

(partial model without unconserved sides chains): PDB file : Tito_3UMC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UMC-query.scw PDB file : Tito_Scwrl_3UMC.pdb: