Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISLQSDQLLEATVGQFMIEADKVAHVQVGNNLEHALLVLTKTGYTAIPVLDPS-YRLHGLIGTNMIMNSIFGLERIEFEKLDQITVEEVMLTDIPRLHINDPIMKGFGMVINNGF--VCVENDEQVFEGIFTRRVVLKELNKHIRSLNK 3OCM Chain:A ((32-160)) -------TLAERSIRSIMTPRTDVSWVNIDDDAATIRQQLTAAPHSFFPVCRGSLDEVVGIGRAKDLVADLITE----------GRVRRNRLRDPIIVHESIGILRLMDTLKRSRGQLVLVADEFGAIEGLVTPIDVFEAIAGEFP----

General information: TITO was launched using: RESULT: Template: 3OCM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 508 -102170 -201.12 -810.87 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -201.12 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.320

(partial model without unconserved sides chains): PDB file : Tito_3OCM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OCM-query.scw PDB file : Tito_Scwrl_3OCM.pdb: