Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVEKCYSCLICG--YKGLIQNPLYKGEYQKTFDICPCCGFEFG-Y-------SEDHDVRLGFIV----TPDHLIEAAFQLYRKQWLESGMVIAHPEDI-PEELKNGN-CLKFEVLL-KQLKKLNLDIENFEISGF 3N6Y Chain:A ((1-137)) --GAQAEVRIDGPIEYGVFESR-SEQNIQQTTEVPAKLGTKFGMRYQLSGKQEGDTPLTLLYLTPGVVTPDGQRHDKFEVVQK------LVPGAPTDVMAYEFTEPHEVVKGEWRLMVFQGDRLLAEKSFDVR--

General information: TITO was launched using: RESULT: Template: 3N6Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 376 10206 27.14 95.38 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 27.14 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.171

(partial model without unconserved sides chains): PDB file : Tito_3N6Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3N6Y-query.scw PDB file : Tito_Scwrl_3N6Y.pdb: