Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAGLLGTP-IGHPAAIALADDAPIITPINSEFGKANRWHTDVTFAANYPAASVLRAVSLPSYGGSTLWANTAAAYAELPEPLKCLTENLWALHTNRYDYVTTKPLTAAQRA-FRQVFEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDVYGQASRVISGAPMEIAG 4Y0E Chain:B ((37-326)) ----ITVEKLGEHIGARVNGIELRGDLSADRVEAIRLALAINKVLVFTEQHHLDDAGQYAFARLLGEPTLPHPTVRSHGTEL-----LNLE-GAANGWHTDVTFVDRIPKASVLRPVTLPSYGGATTWASTVAAYEQLPKPLRSLVDDLWATHTNLY-------------AAYYTEFTSSRYETVHPVVRVHPETGERSLLLGQFVKSFQDLPSAEFASLFQLLQARITKLENTFRWNWRLGDVAIWDNRATQHYGIADFGEQQRELHRVTLAGDVPVDVHGRRSQILLGDASHYSG

General information: TITO was launched using: RESULT: Template: 4Y0E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -108624 for 2265 contacts (-48.0/contact) + 2D Compatibility (PS) -29372 + (NN) -14951 + (LL) 1644 1D Compatibility (HY) -23600 + (ID) 7750 Total energy: -182653.0 ( -80.64 by residue) QMean score : 0.565

(partial model without unconserved sides chains): PDB file : Tito_4Y0E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Y0E-query.scw PDB file : Tito_Scwrl_4Y0E.pdb: