Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MREFGNPLGDRPPLDELARTDLLLDALAEREEVDFADPRDDALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRRRARRS----LAAVGSVAAALLVLSGFGAVVADARP-GDLLYGLHAMMFNRSRVSDDQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVGNSWTPLAPVVEPPTPPTPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH 4HTP Chain:A ((7-237)) ----SQTVASHVPFADLCS---TLERIQKSKG---RAEKIRHFREFLDSWRKFHDALHKNHKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYGDFAMIAYFVLKPRCL-------QKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLK---------------------LGVSQQTIFSVFHNDAAELHNVT---------------TDLEKVCRQLHDPSVGLSD------------------------------

General information: TITO was launched using: RESULT: Template: 4HTP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -8721 for 1638 contacts (-5.3/contact) + 2D Compatibility (PS) -23834 + (NN) -13729 + (LL) 1560 1D Compatibility (HY) -7200 + (ID) 1350 Total energy: -53274.0 ( -32.52 by residue) QMean score : 0.203

(partial model without unconserved sides chains): PDB file : Tito_4HTP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HTP-query.scw PDB file : Tito_Scwrl_4HTP.pdb: