Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKS--NSKVGQSMVGLAWILSSV--FAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL 4LDL Chain:A ((221-447)) -------------------------------------------------------------------------------ITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATH------QEAI--NCYAEETCCDFFTNQAYAIASSIVSFYVPLVIM-------VFVYSRVFQEAKRQLQ---KFALKEHKALKTLGIIMG---TFTLCWLPFFIVNIVHVIQDNLIRK---EVYILLNWIGYVNSGFNPLIYCRSPD

General information: TITO was launched using: RESULT: Template: 4LDL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -172074 for 1535 contacts (-112.1/contact) + 2D Compatibility (PS) -21882 + (NN) -208 + (LL) 7224 1D Compatibility (HY) -27600 + (ID) 2850 Total energy: -217390.0 ( -141.62 by residue) QMean score : 0.251

(partial model without unconserved sides chains): PDB file : Tito_4LDL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LDL-query.scw PDB file : Tito_Scwrl_4LDL.pdb: