Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKHTAITTFILLGLTEDPQLQVLLFMFLFITYMLSVTGKLTIIALTMLDPHLKTPMYFFLQNLSFLEI-----SFTATCVPRFLYSISTGNKIITYNACVIQLFFADLFGVTEFFLLATMSYDRYVAICKPLHYMAIMSNKVCKTMVICCWMAALMIILPPLSLGFHLEFCDSNVINHFGCDALPILKIPCSDTSLIEQMVVASAVLTFIITLVCVVLSYTYIIRTILKFPSVQQKKKAFSTCSSHIT-----------VVSITYGSCIFIYIKPSAKEEVNINKGVSVLISSISPMLNSFIYTLRNEQVKQAFHDSLKKIAFRLKK 3C9L Chain:A ((33-315)) -----------------EPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTT-----LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAF-TWVMALACAAPPL-VGWS-RYIPEGMQCSCGID----YYTPHEETN-NESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNDDE-

General information: TITO was launched using: RESULT: Template: 3C9L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -184663 for 2073 contacts (-89.1/contact) + 2D Compatibility (PS) -27243 + (NN) -8378 + (LL) 3016 1D Compatibility (HY) -24800 + (ID) 3200 Total energy: -245268.0 ( -118.32 by residue) QMean score : 0.180

(partial model without unconserved sides chains): PDB file : Tito_3C9L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C9L-query.scw PDB file : Tito_Scwrl_3C9L.pdb: