Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCT-QVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK 4XT3 Chain:A ((48-316)) -----------------------------YGVVFLFGSIGNFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDH----ASVPCTLLTACFYVAMFASLCFITEIALDRYYAIVYMRYRPVKQ----ACLFSIFWWIFAVIIAIPHF----MVVTKKDNQCMTDYDYLEVSYPIILNVELMLGAFVIPLSVISYCYYRIS-----RIVAVSQSRHKGRIVRVLIAVVLVFIIFWLPYHLTLFVD-TLKLLKWISSSCEFERSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQELHCLLAE----------------------

General information: TITO was launched using: RESULT: Template: 4XT3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -209435 for 1988 contacts (-105.3/contact) + 2D Compatibility (PS) -27158 + (NN) -8261 + (LL) 6712 1D Compatibility (HY) -32400 + (ID) 3750 Total energy: -274292.0 ( -137.97 by residue) QMean score : 0.229

(partial model without unconserved sides chains): PDB file : Tito_4XT3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XT3-query.scw PDB file : Tito_Scwrl_4XT3.pdb: