Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTTEYVAEILNELHNSAAYISNEEA----DQLADHILSSHQIFTAGAGRSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAKSLHGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYDAVILKLMEKKGLDSETMFTHHANLE 1JEO Chain:A ((20-179)) -------------------FYTNDEWKNKLDSLIDRIIKAKKIFIFGVGRSGYIGRCFAMRLMHLGFKSYFVGETTTPSYEKDDLLILISGSGRTESVL-TVAKKAKNINNNIIAIVCECGNVVEFADLTI-----PLEVKKSKY---LPMGTTFEETALIFLDLVIAEIMKRLNLDESEIIKRHCNL-

General information: TITO was launched using: RESULT: Template: 1JEO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 727 -107155 -147.39 -686.89 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -147.39 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_1JEO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JEO-query.scw PDB file : Tito_Scwrl_1JEO.pdb: