Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDQSCVRIMTEWDIVAARQLGRNVAKELGFGTVDQ-ARITTAISELARNIYLYA----GKGQIGIEQVADRGKKGLKIIAEDQGPGIPDIRKVMEDGFSTSGGL---GAGLPGVKRLMDEFSLNSVAGEGTEIQAIKWLR 1THN Chain:A ((33-132)) --------------------------------TMDELTEIKTVVSEAVTNAIIHGYNNDPNGIVSISVIIEDGVVHLTV--RDEGVGIPDIEEARQPLFTTKPELERSGMGFTIMENFMDEVIVESEVNKGTTV-------

General information: TITO was launched using: RESULT: Template: 1THN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 321 -28817 -89.77 -313.22 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -89.77 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_1THN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1THN-query.scw PDB file : Tito_Scwrl_1THN.pdb: