Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTLRLNNVTLEMAAYQEESEPKRKIAFTLNVTS-ETYHDIAVLLY--EKTFNVEVP--E--RDLAFRGEMTNYSTSLTNLYEPGAVSEFYIEITEIDKNADS 4GDZ Chain:A ((104-167)) -------------SDIKTSTDKRGNINCSFSIQGIGISAQIFLTLTNGDNNATVTINPNFNSNTMTLSGSLLPLNQS--------------------------

General information: TITO was launched using: RESULT: Template: 4GDZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 173 -15523 -89.73 -272.32 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -89.73 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_4GDZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GDZ-query.scw PDB file : Tito_Scwrl_4GDZ.pdb: