Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAINKAVSIDTAFQTIMQELRERSARFLGTKQAVSEEKAEFDCPYCKDRGIVVYRVHKDTSWHLDEQLDLMVPDDMVSEDDFLLGKVCTPDKASEWKDTYSKQCECVRRKKIARLMAASGITEEFEKLLFGNFITDGKPDMIKDAYECAVEYYKDFQKIKGERQNSIALLGQPGSGKTHLLTAIMNNLIKKK-SVHCMYFPYVEGMGDLKANFDN--LEAKLDAMRKVEVLFIDDLFKPINGQPRATDWQVEQI-QSVLNYRYLNHKPLLISSELTIDEILDIDEALGSRIHQMCRDYIVIIRGDRMQLNHRLGDWE 2W58 Chain:A ((32-168)) ---------------------------------------------------------------------------------------------------------------------------------------DGRIKAIRFAERFVAEYEP------GKKMKGLYLHGSFGVGKTYLLAAIANELAKRNVSSLIVYVP--ELFRELKHS---QTMNEKLDYIKKVPVLMLDDL-----GAE---SWVRDDVFGPILQYRMFENLPTFFTSNFDMQQL-------------------------------------

General information: TITO was launched using: RESULT: Template: 2W58.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 437 -26793 -61.31 -219.61 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -61.31 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.549

(partial model without unconserved sides chains): PDB file : Tito_2W58.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W58-query.scw PDB file : Tito_Scwrl_2W58.pdb: