Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVL----SEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH 2YCZ Chain:A ((28-298)) -----------------------------------------------GNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQD-PGCCDFVT---NRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRKID------RASKRKRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRLLAF-----------------

General information: TITO was launched using: RESULT: Template: 2YCZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -222676 for 1954 contacts (-114.0/contact) + 2D Compatibility (PS) -26534 + (NN) 2414 + (LL) 3356 1D Compatibility (HY) -23600 + (ID) 4200 Total energy: -271240.0 ( -138.81 by residue) QMean score : 0.303

(partial model without unconserved sides chains): PDB file : Tito_2YCZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YCZ-query.scw PDB file : Tito_Scwrl_2YCZ.pdb: