Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPAD---KFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD 3ALN Chain:A ((15-307)) -------------------------------------------QHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQ------------------------------YDVRSDVWSLGITLYELATGRFPYPKW-------TQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQ

General information: TITO was launched using: RESULT: Template: 3ALN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -175164 for 1958 contacts (-89.5/contact) + 2D Compatibility (PS) -26415 + (NN) -10719 + (LL) 2996 1D Compatibility (HY) -32000 + (ID) 7350 Total energy: -248652.0 ( -126.99 by residue) QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_3ALN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ALN-query.scw PDB file : Tito_Scwrl_3ALN.pdb: