Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MILRRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSLTKDLANKFELPPMVSVNDSNHETAFTVSID-AKEAKTGISAFERHLTIELLCKDTTKPSDFVRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSVICEIMK-EDGSMARRGDKFLSDFAIKHNLKTLYVSDLISYRLENESLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKFKGAKTHDLAPLVRFHPIKEDFDFLTTGAFEAFFKALEYLKREGGYLIFMNTHSEQNNIVKDFGIGALVLKNLGVKDFRLLSSCEDRQYKALSGFGLKLVETISL 1TKU Chain:A ((4-201)) -IFTPIEEALEAYKNGEFLIVMDDEDRENEGDLIMAAELITQEKMAFLVRYSSGYVCVPLSEERANQLELPPMLA------GTAYTITCDFAEGTTTGISAHDRALTTRSLANPNSKPQDFIKPGHILPLRAVPGLLKKRRGHTEAAVQLSTLAGLQPAGVICELVRDEDGLMMRLDDCI--QFGKKHGIKIININQLVEYISK----------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1TKU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -134881 for 1617 contacts (-83.4/contact) + 2D Compatibility (PS) -20824 + (NN) -9631 + (LL) 10856 1D Compatibility (HY) -17600 + (ID) 4850 Total energy: -176930.0 ( -109.42 by residue) QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_1TKU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TKU-query.scw PDB file : Tito_Scwrl_1TKU.pdb: