Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLKLRLTHLWYKLLMKLGLKSDEVYYIGGSEALPPPLSKDEEQVLLMKLPNGDQAARAILIERNLRLVVYIARKFENTGINIEDLISIGTIGLIKAVNTFNPEKKIKLATYAS--------RCIEN-------------EILMYLRR----NNKIRSE---------------------------VSFDEPLNIDWDGNELLLSDVLGTDDDIITKDIEANVD-KKLLKKALEQLNEREKQIMELRFGLVGEEEKTQKDVADMMGISQSYISRLEKRIIKRLRKEFNKMV 5IPN Chain:F ((63-315)) ------------------------------GEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNERITSVDTPLGGD---SEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLRE------

General information: TITO was launched using: RESULT: Template: 5IPN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 512 -51096 -99.80 -255.48 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain F : 0.70 3D Compatibility (PKB) : -99.80 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.526

(partial model without unconserved sides chains): PDB file : Tito_5IPN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IPN-query.scw PDB file : Tito_Scwrl_5IPN.pdb: