Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLNNRNVLLCVSGGIAVYKACALTSKLVQAGANVKVIMTESACRFVSPLTFQALSRHEVYTDTFKEQNPSVISHIDAADWADLIIVAPATANVIGKLANGIADDMLTTTLLAATAPVWIAPAMNVHMYDHPAVKRNISVLYQDGYCFIEPSEGYLACGYVGKGRLEEPENIVKLAEKHFAEETSAPLEGKHVVITAGPTREAIDPVRFFTNKSTGKMGYALAEAAVQLGARVILISGPVSLDQPKGLAEFIPVQSAADMREAVLSVYDASDIVIKTAAVADFTPKTVFDHKMKKQDGGMTLELKRTVDILKELGEKKKEQ-ILVGFAAETQDIEHYARKKLAAKNLDLIVANDVKANGAGFGADTNIVTIFFKDGHKRELPIMSKLDVSFEILQEIAALSKQTGERS 1U7Z Chain:A ((6-225)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKHLNIMITAGPTREPLDPVRYISDHSSGKMGFAIAAAAARRGANVTLVSGPVSLPTPP-FVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKI----DELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDK-VLPLERKELLGQLLLDEIVTRYDEKNR--

General information: TITO was launched using: RESULT: Template: 1U7Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1203 -127295 -105.81 -600.45 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -105.81 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.556

(partial model without unconserved sides chains): PDB file : Tito_1U7Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1U7Z-query.scw PDB file : Tito_Scwrl_1U7Z.pdb: