Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKLFKEVKLEELENQKGSGLGKAQCAALWLQCASGGTIGCGGGAVACQNYRQFCR 1OV9 Chain:A ((13-29)) LRAYARELTIEQLEEAL---------------------------------------

General information: TITO was launched using: RESULT: Template: 1OV9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 14 -1866 -133.29 -109.76 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -133.29 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.988

(partial model without unconserved sides chains): PDB file : Tito_1OV9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OV9-query.scw PDB file : Tito_Scwrl_1OV9.pdb: