Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLSQTLLEMTEQMIEVAEKGADRYQEGKNSNHSYDFFETIKPAVEENDELAARWAEGALELIKVRRP-----KYVHKEQIEAVKDNFLELVLQSYVHHIHKKRFKDITESVLYTLHAVKDEIAREDSR 2ETS Chain:A ((15-122)) -------DLVESLIYEVNNMQQNFENVKSQQQDHDFYQTVKPYTEHIDSI--------LNEIKLHREFIIEVPYMNSRKFELLIANIEQLSVECHFKRTSRKLFIEKLKSVQYDLQNILDGVT-----

General information: TITO was launched using: RESULT: Template: 2ETS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 315 -12917 -41.01 -125.41 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -41.01 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.664

(partial model without unconserved sides chains): PDB file : Tito_2ETS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ETS-query.scw PDB file : Tito_Scwrl_2ETS.pdb: