Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIQNPYTAYQQNSVNTATPGELTLMLYNGCLKFIRLAAQAIEN-DDMERKN---ENLIKAQNIIQELNFTLN--RNIELSASMGAMYDYMYRRLVQAN-IKNDTGMLAEVEGYVTDFRDAWKQAIQSERKDRHGSGGIA 1ORY Chain:A ((6-119)) -------EAYFQNQVETATPLEQIILLYDKAIECLERAIEIYDQVNELEKRKEFVENIDRVYDIISALKSFLDHEKGKEIAKNLDTIYTIILNTLVKVDKTKEELQKILEI---LKDLREAWEE----------------

General information: TITO was launched using: RESULT: Template: 1ORY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 291 -19493 -66.98 -182.17 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -66.98 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_1ORY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ORY-query.scw PDB file : Tito_Scwrl_1ORY.pdb: