Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFNQVMLVGRLTKDPDLRYTSAGAAVAHVTLA-VNRSFKNASGEI---EADYVNCTLWRKTAENTALYCQKGSLVGVSGRIQTRSYENEEGVNVYVTEVLADTVRFMDPKPREKAAD 1X3G Chain:A ((7-106)) ----ITVVGNLTADPELRFTPSGAAVANFTVASTPRMFDR----WKDGEALFLRCNIWREAAENVAESLTRGSRVIVTGRLKQRSFETREGEKRTVVEVEVDEI-------------

General information: TITO was launched using: RESULT: Template: 1X3G.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 322 -8327 -25.86 -90.51 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -25.86 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.576

(partial model without unconserved sides chains): PDB file : Tito_1X3G.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X3G-query.scw PDB file : Tito_Scwrl_1X3G.pdb: