Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYIMKQSGWLELICGSMFSGKSEELIRRVKRATYAKQEVRVFKPVIDNRYSEAAVVSHNGTSMTSYAISSAADIWDHISESTDVVAVDEVQFFDQEIVEVLSSLADKGYRVIAAGLDMDFRGEPFGVVPNIMAIAESVTKLQAVCSVCGS-PASRTQRLIDGKPASYDDPVILVGAAESYEARCRHHHEVPGKSKK 2ORW Chain:A ((2-174)) ------SGKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPK-----HSTMIVS----GVEAHVIERPEEMRKYIEEDTRGVFIDEVQFFNPSLFEVVKDLLDRGIDVFCAGLDLTHKQNPFETTALLLSLADTVIKKKAVCHRCGEYNATLTLKVAGGEEE------IDVGGQEKYIAVCR-----------

General information: TITO was launched using: RESULT: Template: 2ORW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 830 -105479 -127.08 -647.11 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -127.08 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.378

(partial model without unconserved sides chains): PDB file : Tito_2ORW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ORW-query.scw PDB file : Tito_Scwrl_2ORW.pdb: