Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKNQNRIRNRWELITCGLGGHVTYAPDDAALAARLRASTGLGEVWRCLRCGDFALGGP-----QGRGAPEDAPLIMRGKALRQAIII---RALGVERLVRALVLALAAWAVWEFRGARGAIQATLDRDLPVLRAAGFKVDQMTVIHALEKALAAKPSTLALITGMLAAYAVLQAVEGVGLWLLKRWGEYFAVVATSIFLPLEVHDLAKGITTTRVVTFSINVAAVVYLLISKRLFGVRGGRKAYDVERRGEQLLDLERAAMLT 2FEZ Chain:A ((12-96)) ----------------------------------------------------DFGLLGPLQMTIDGTPVPSGTP---KQRAVLAMLVINRNRPVGVDALITAL------WEEWPPSGARASIHSYVSNLRKLLGGAG--IDPRVVLAA--------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2FEZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -28509 for 440 contacts (-64.8/contact) + 2D Compatibility (PS) -8094 + (NN) -2079 + (LL) 16248 1D Compatibility (HY) -6400 + (ID) 1400 Total energy: -30234.0 ( -68.71 by residue) QMean score : 0.424

(partial model without unconserved sides chains): PDB file : Tito_2FEZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2FEZ-query.scw PDB file : Tito_Scwrl_2FEZ.pdb: