Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLV--DGLKAAGAAKIYVAESDLVDKYLITPAVDVLAGLAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAAGAGEQVSVEVPAAAENAARITAR--EPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYYPGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEAIKARKG 2A1U Chain:A ((23-333)) ----LVIAEHANDSLAPITLNTITAATRLGGEVSCLVA--GTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDA--AATSGGSASSE-KASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK--

General information: TITO was launched using: RESULT: Template: 2A1U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -202401 for 2659 contacts (-76.1/contact) + 2D Compatibility (PS) -33190 + (NN) -11553 + (LL) 748 1D Compatibility (HY) -25200 + (ID) 6700 Total energy: -278296.0 ( -104.66 by residue) QMean score : 0.563

(partial model without unconserved sides chains): PDB file : Tito_2A1U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2A1U-query.scw PDB file : Tito_Scwrl_2A1U.pdb: