Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKFDISVLSVAPL-------RQG--ETMKQGIDSAVSLAKAVDNMGYKRIWFAEHHNHD------AYASAATVSIVQHILANTKDIRVGSGGIMLPNHSPLIVAEQFGTLETLYPNRVDLALGRAPGTDQKTADVIRRSN---HNGVFFFEREVNDILRFVGDK---------------------S-----VQGE----VRAYPGIGTHVPVFVLGSSTDSAEIAAKLGLPYAFGAQFSPHSMEEALSIYRENFQPSSYL-QEPYVIACINVIAAESIDEASFISASHLQ------------VYIDIYT---N---N---------LSKLIPPTENFLESL-------SQFELEIL-H---SRLGYTIMGDRETIRRELIDFQQMYHADELIVLSNIYELSKEIQSYEILKQVVDELFKKRMEQL 3SDO Chain:A ((7-419)) RKHIHFGVLIQGAGANMNAWKHPSVPPDASVNFDFYVDRARRAENAGIAFAFIADSAYVTPKSAPHFLNRFEPISLLSALAVLTSKIGLV-GTMSSSYSEPYNVARQFASLDLISGGRAGWNVVTS--SIEGTGKNYGRPHPDHAQRYAIAAEHLDVVQGLWDSWDDDALVRDRATGRFFDPDKLHRLDHRGRFFSVEGPLNIRRSPQGQPVIFQAGSSDDGIDLAGRSADAVFSNG-STFDEARVFYRRVKAAAAAAGRNPDHVKVFPGIGPIVGATQQEADDKYRQVRDLLSPREALAYLSHFFQQHDFSVYPLDGPFPDIGTLGSDGFQSTTDNIKRLARERKLTLREVAYEVSTRRSNIGTSEAFIGTPEAVASEMIRWVDEGAADGFMLGLPVT-----GFGLDDFVDHVLPVLSAR----

General information: TITO was launched using: RESULT: Template: 3SDO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1675 -186701 -111.46 -572.70 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -111.46 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.432

(partial model without unconserved sides chains): PDB file : Tito_3SDO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SDO-query.scw PDB file : Tito_Scwrl_3SDO.pdb: