Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLAVNFTAFFYNLNISNLTRQVNKMKMDELEKVMIVEGKSDKEKIESVLN-EPMRIICTNGTIS--------QLRLEELADE-LYDKDVYILVDADESGEKLRKQLKREFNE--ACHLHVDRAY---KEVAAAPRHHIASVLLRANLNVHTIFLERKSRGV 1VDD Chain:A ((76-199)) --------------------------SRDQRTICVVEEPGDVIALERSGEYRG-LYHVLHGVLSPMNGVGPDKLHIKPLLPRVGQGMEVILATGTTVEGDATALYLQRLLEPLGAAISRIAYGVPVGGSLEYTDEVTLGRALTGRQTVSKP----------

General information: TITO was launched using: RESULT: Template: 1VDD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 396 -3262 -8.24 -29.93 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -8.24 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.436

(partial model without unconserved sides chains): PDB file : Tito_1VDD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VDD-query.scw PDB file : Tito_Scwrl_1VDD.pdb: