Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCN-RKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWR-RKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES 4AU8 Chain:A ((5-292)) ----SQKYEKLEKIGEGTYGTVFKAKNRETH---EIVALKRV---------PSSALREICLLKELKHKNIVRLHDVLH----KLTLVFEFCDQDLKKYFDSC--NGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR--SAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP-YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD-

General information: TITO was launched using: RESULT: Template: 4AU8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -178104 for 2219 contacts (-80.3/contact) + 2D Compatibility (PS) -28442 + (NN) -7722 + (LL) 872 1D Compatibility (HY) -31600 + (ID) 7750 Total energy: -252746.0 ( -113.90 by residue) QMean score : 0.495

(partial model without unconserved sides chains): PDB file : Tito_4AU8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AU8-query.scw PDB file : Tito_Scwrl_4AU8.pdb: