Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKLCKQLIETLVESM-GITVPVAIHLDHG-HYDDALECIEVGYTSIMFDGSHLPVEENLEKAREVVAKAHAKGISVEAEVGTIGGEEDGIVGKGELAPIEDAKAM-VETGIDFLAAGIGNIHGPYPAN-WEGLDLDHLKKLTEAVPGFPIVLHGGS---------------------GIPDDQIQEAIKLGVAKVNVNTECQLAFCQATRDYAVEFNANEAEYMKKKLFDPRKFLKPGFDAITEAVEERIDVFGSANKA 2ISW Chain:A ((2-307)) -PLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPVILQCSRGALKYSD-MIYLKKLCEAA--LEKHPDIPICIHLDHGDTLESVKMAIDLGFSSVMIDASHHPFDENVRITKEVVAYAHARSVSVEAELGTL----------VQLTEPQDAKKFVELTGVDALAVAIGTSHGAYKFKS--RLAIDRVKTISDL-TGIPLVMHGSSSVPKDVKDMINKYGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVE---------HPEKFDPRDYLGPGRDAITEMLIPKIKAFGSAGHA

General information: TITO was launched using: RESULT: Template: 2ISW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -119534 for 2361 contacts (-50.6/contact) + 2D Compatibility (PS) -30342 + (NN) -20304 + (LL) 1456 1D Compatibility (HY) -20000 + (ID) 5650 Total energy: -194374.0 ( -82.33 by residue) QMean score : 0.642

(partial model without unconserved sides chains): PDB file : Tito_2ISW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ISW-query.scw PDB file : Tito_Scwrl_2ISW.pdb: