Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQDLYQLIGEKLNDIIPGEWTKIYLYAEVLDDSTMVLFHFRTPENNQIIYSQDIPSHYNV-SKDIFKTLLRELRELFEELRTEHRNNNDDVWTNLTLTLDRSGEFQLDYNYDDILASELDGYE-RIAIWE-YKNLGILPEDEDDKEFVISYLGL 4P55 Chain:A ((2-105)) -----------------SEWLTDFI-IDALDSGRFWGVGWLDEQKRIFTVP--GRNRRERMPEG-FDDFYEAFLEERRRHGLPEIPETETGLGCFGRLLRTANRARQERPF------TIYKGKMKLNRWIMT----------------------

General information: TITO was launched using: RESULT: Template: 4P55.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 365 -43418 -118.95 -429.88 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -118.95 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.476

(partial model without unconserved sides chains): PDB file : Tito_4P55.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P55-query.scw PDB file : Tito_Scwrl_4P55.pdb: