Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRYRTLLFDVDDTILDFQAAEALALRLLFEDQNIPLTND-MKAQYKTINQGL---WRAF--EEGKMTRDEVVNTRFSALLKEYGYEAD---GALLEQKYRRFL-EEGHQLIDGAFDLISNLQ-QQFDLYIVTNGVSHTQYKRLRDSGLFPFFKDIFVSEDTGFQKPMKEYFNYVFERIPQFSAEHTLIIGDSLTADIKGGQLAGLDTCWMNPDMKPNVP---EIIPTYEIRKLEELYHILNIENTVSC 3K1Z Chain:A ((1-239)) ---MRLLTWDVKDTLLRLRHPLGEAYATKARAHGLEVEPSALEQGFRQAYRAQSHSFPNYGLSHGL-TSRQWWLDVVLQTFHLAGVQDAQAVAPIAEQLYKDFSHPCTWQVLDGAEDTLRECRTRGLRLAVISNFDRR-LEGILGGLGLREHFDFVLTSEAAGWPKPDPRIFQEALRLA-HMEPVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVRDSVPKEHILPSLAHLLPALDCLE----

General information: TITO was launched using: RESULT: Template: 3K1Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1103 -148931 -135.02 -661.92 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -135.02 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3K1Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3K1Z-query.scw PDB file : Tito_Scwrl_3K1Z.pdb: