Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEHQVRCAVLGLGRLGY-YHAKNLVTSVP-GAKLVCVGDPLKGRAEQVARELGIEKWSEDPYEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGA------PPAEFI--KHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRTSPYGHDIRAEVIGTEGSI-FIGTLRHQHVTILSAKGSSFDIIPDFQTRFHEAYCLELQHFAECVRNGKTPI-VTDIDATINLEVGIAATNSFRNGMPVQLDVKRAYTGM 1ZH8 Chain:A ((16-338)) -LRKIRLGIVGCGIAARELHLPALKN-LSHLFEITAVTSRTRSHAEEFAKMVGNPAVFDSYEELLESGLVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSEKTVYIAENFRHVPAFWKAKELVESGAIGDPVFMNWQIWVGMDENNKYVHTDWRKKPKHVGGFLSDGGVHHAAAMRLILGE-IEWISAVAKDL-SPL---LGGMDFLSSIFEFENGTVGNYTISYSLKGN--ERFEITGTKGKISISWDKI----VLN-------EEE--MKVPQENSYQKEFEDFYQVVAEGKPNDLGSPVQALKDLAFIEACVRSAGNKVFVSS---------

General information: TITO was launched using: RESULT: Template: 1ZH8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1778 -187892 -105.68 -604.15 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -105.68 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_1ZH8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZH8-query.scw PDB file : Tito_Scwrl_1ZH8.pdb: