Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLPSSLKEEITSFVLEDAKIREGFREFVAFINEHEIPFYVISG-GMDFFVYPLLEGIVEKDRIYCNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSEPNQYIIMIGDSVTDVEAAKLSDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK 1U7P Chain:A ((1-164)) MTRLPKLAVFDLDYTL---------WPFWVDTH---------------------VDPPFHKSSDGTVRDRRGQNIQLYPEVPEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLGKYFIQREIYPGSKVTHFERLHHKTGV------------------PFSQMVFFDDENRNIIDVG----------------RLGVTCIHIRDGMS----LQTLTQGLETFAKAQAGL----

General information: TITO was launched using: RESULT: Template: 1U7P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 819 -105687 -129.04 -648.38 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -129.04 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.308

(partial model without unconserved sides chains): PDB file : Tito_1U7P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1U7P-query.scw PDB file : Tito_Scwrl_1U7P.pdb: